SSRI's antidepressant effect..is a MYTH!
Question:
– Hide quoted text — Show quoted text – > Peter Jennings: "Just when is the drug actually making a difference? > Antidepressants are very popular these days: sales are up 17% from > just last year. Millions and millions of prescriptions now are being > written to battle depression and mood swings. Tonight, are these drugs > really doing everything that people think they are? Here’s ABC’s > Deborah Amos " > Deborah Amos: "These depression fighting pills are 60 – 70% effective > in bringing relief according to the medical literature. But Thomas > Moore, who studies drugs at George Washington University, says the > numbers are misleading" > Thomas Moore: "Millions of Americans believe that the benefits of > these drugs are much greater than they are" > Deborah Amos: "To investigate, Moore analyzed all drug company tests > on five major drugs submitted to the FDA prior to market approval: for > Paxil, Zoloft, Effexor, Serzone and Prozac. The effectiveness of the > drug was measured against a placebo or sugar pill." > Thomas Moore: "The effect of antidepressants drugs on depression is > only very little different than the effect of a completely inactive > placebo." > Deborah Amos: "The highlight of Moore’s finding is the case of Prozac > with more than $2 billion dollars in U.S. Sales. About 90% of Prozac’s > overall effectiveness is about the same as patients taking nothing > stronger than a sugar pill. But the label for antidepressant drugs, > the prescribing detail for doctors, usually do not spell out the small > overall differences between the drug and the placebos." > Thomas Moore: "At the very least the FDA product labeling should > include a more balanced picture of all the information they have > received about the drug, – about all the clinical trials." > Deborah Amos: ""The FDA says it does not put that kind of detail on > the label because it is not helpful in predicting individual outcomes. > So what does it all mean for patients, when a placebo can have almost > the same benefits as a dug, and particularly, when a drug can have > unpleasant side-effects. > (a psychologist from the University of Conn., who has teamed up with > Thomas Moore.) > "It suggests that the frontline of treatment for depression should be > psychological rather than chemical." > Deborah Ames: "The problem is that good therapy is expensive and not > always available. Pills are cheaper and more easily available. Deborah > Ames, ABC News, New York."
Response:
placebos have side effetcs too!
– Hide quoted text — Show quoted text -> Peter Jennings: "Just when is the drug actually making a difference? > Antidepressants are very popular these days: sales are up 17% from > just last year. Millions and millions of prescriptions now are being > written to battle depression and mood swings. Tonight, are these drugs > really doing everything that people think they are? Here’s ABC’s > Deborah Amos " > Deborah Amos: "These depression fighting pills are 60 – 70% effective > in bringing relief according to the medical literature. But Thomas > Moore, who studies drugs at George Washington University, says the > numbers are misleading" > Thomas Moore: "Millions of Americans believe that the benefits of > these drugs are much greater than they are" > Deborah Amos: "To investigate, Moore analyzed all drug company tests > on five major drugs submitted to the FDA prior to market approval: for > Paxil, Zoloft, Effexor, Serzone and Prozac. The effectiveness of the > drug was measured against a placebo or sugar pill." > Thomas Moore: "The effect of antidepressants drugs on depression is > only very little different than the effect of a completely inactive > placebo." > Deborah Amos: "The highlight of Moore’s finding is the case of Prozac > with more than $2 billion dollars in U.S. Sales. About 90% of Prozac’s > overall effectiveness is about the same as patients taking nothing > stronger than a sugar pill. But the label for antidepressant drugs, > the prescribing detail for doctors, usually do not spell out the small > overall differences between the drug and the placebos." > Thomas Moore: "At the very least the FDA product labeling should > include a more balanced picture of all the information they have > received about the drug, – about all the clinical trials." > Deborah Amos: ""The FDA says it does not put that kind of detail on > the label because it is not helpful in predicting individual outcomes. > So what does it all mean for patients, when a placebo can have almost > the same benefits as a dug, and particularly, when a drug can have > unpleasant side-effects. > (a psychologist from the University of Conn., who has teamed up with > Thomas Moore.) > "It suggests that the frontline of treatment for depression should be > psychological rather than chemical." > Deborah Ames: "The problem is that good therapy is expensive and not > always available. Pills are cheaper and more easily available. Deborah > Ames, ABC News, New York."
Response:
be careful with this. this report only serves to bolster the stigma against those suffering from severe mental illness. what the report probably does not distinguish is responsiveness of medications for individuals suffering severe depression (i.e., biological, chemical-based depression). for myself, i would not be alive if not for the medication i currently take (parnate, an maoi). thank God for this medication. incidentally, i tried several ssris (prozac, paxil, effexor) and had no benefit from any of them.
Response:
> be careful with this. this report only serves to bolster the stigma against > those suffering from severe mental illness. what the report probably does not > distinguish is responsiveness of medications for individuals suffering severe > depression (i.e., biological, chemical-based depression). > for myself, i would not be alive if not for the medication i currently take > (parnate, an maoi). thank God for this medication. incidentally, i tried > several ssris (prozac, paxil, effexor) and had no benefit from any of them.
Sorry, even the testing for the initial approval of SSRI’s clearly demonstrated that they are barely more effective then placebos WHEN the placebos were engineered to cause side effects. SSRI’s are marketing, nothing more! Mood not bright? Try zippyium yes, zippyium the little pill with the BIG effect! Jingle: Mood not bright, try zippyium tonight, its zippyium for me, yessiree, zippyium zippyium, zippyium for me.
Response:
> "What is even more shocking was the discovery that > active placebos may be 100 percent as effective as > antidepressants.:
I think this quote says it best……Active placebo? That has to be the oxymoron of the decade.
Response:
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